Single-cell spatiotemporal dissection of the human maternal–fetal interface

A study published in Nature on April 8, 2026, presents a single-cell multiomic atlas of the human maternal–fetal interface during pregnancy, revealing cell types, spatial niches, and transcriptional programs. The research identifies specific cell types linked to pre-eclampsia, spontaneous preterm birth, and miscarriage, offering insights into pregnancy-related complications.