Dossier
AcrVA2
Coverage of AcrVA2 in the Nexus archive.
- Translation-dependent degradation of cas12 mRNA triggered by an anti-CRISPR
The anti-CRISPR protein AcrVA2 disrupts Cas12a biogenesis by inducing co-translational degradation of cas12 mRNA. This mechanism highlights a novel regulatory pathway in CRISPR systems.