Dossier
CRISPR-Cas12a2
Coverage of CRISPR-Cas12a2 in the Nexus archive.
- RNA-triggered cell killing with CRISPR–Cas12a2
CRISPR-Cas12a2 enables RNA-triggered killing of eukaryotic cells through DNA shredding, allowing selective elimination of virus-infected or mutation-bearing cells. This technology has potential applications in gene expression and cell targeting. The research was published in Nature on May 6, 2026.