Dossier
GLP-1 resistance
Coverage of GLP-1 resistance in the Nexus archive.
- Scientists discover why ozempic may not work for some people
Scientists have identified genetic variants that may reduce the effectiveness of GLP-1 drugs for treating Type 2 diabetes in about 10% of the population. These variants appear to cause 'GLP-1 resistance,' making carriers less likely to achieve healthy blood sugar targets during clinical trials of these medications.
- Why Ozempic doesn’t work for everyone: Scientists just found a hidden reason
A new study identifies that 10% of people may not respond to Ozempic and Wegovy due to genetic variants causing GLP-1 resistance. The condition involves elevated GLP-1 hormone levels without proper response to the drugs.