Dossier
Spermidine
Coverage of Spermidine in the Nexus archive.
- A common constipation drug shows surprising power to protect kidneys
A common constipation drug called lubiprostone may help slow chronic kidney disease by preserving kidney function. Researchers found this effect in a clinical trial involving 150 patients with moderate CKD. The drug works by changing gut bacteria to produce spermidine, which is linked to healthier mitochondria and reduced kidney damage.