Dossier
tissue-nonspecific alkaline phosphatase
Coverage of tissue-nonspecific alkaline phosphatase in the Nexus archive.
- Glycerol-driven TNAP activation in thermogenesis and mineralization
Glycerol acts as an allosteric activator for tissue-nonspecific alkaline phosphatase (TNAP), linking it to thermogenesis and mineralization processes. This activation drives the futile creatine cycle, a metabolic mechanism with potential implications in energy regulation.