Cancer drugs
Coverage of Cancer drugs in the Nexus archive.
- Prediction market wagering on drug approvals draws fire from researchers
Betting platforms Kalshi and Polymarket are allowing users to wager on FDA drug approvals and clinical trial outcomes, sparking criticism from researchers, doctors, and patients over risks to scientific integrity and public trust. Critics argue prediction markets could influence trial behavior and enable insider trading, while Kalshi claims they offer valuable insights and have safeguards against insider participation.
- Lokayukta directs Karnataka govt. to act on cancer drug availability
The Lokayukta has directed the Karnataka government to take action regarding the availability of cancer drugs.
- Scientists finally uncover why promising cancer drugs keep failing
Scientists have identified why BET inhibitors, a class of cancer drugs, have failed in clinical trials. The research shows BRD2 and BRD4 proteins have distinct roles in gene activation, with BRD2 acting as a 'stage manager' and BRD4 triggering gene activation. Blocking both proteins simultaneously disrupts the process, leading to inconsistent drug effectiveness.