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Gene activation

Coverage of Gene activation in the Nexus archive.

Earliest in view: Apr 10 · 03:42 UTCMost recent: Apr 10 · 03:42 UTC
Co-mentioned in this coverage
BET inhibitorstopic1BRD2topic1BRD4topic1Cancer drugstopic1
Recent coverage
  • HEALTHApr 10 · 03:42 UTCSCIENCE DAILY
    Scientists finally uncover why promising cancer drugs keep failing

    Scientists have identified why BET inhibitors, a class of cancer drugs, have failed in clinical trials. The research shows BRD2 and BRD4 proteins have distinct roles in gene activation, with BRD2 acting as a 'stage manager' and BRD4 triggering gene activation. Blocking both proteins simultaneously disrupts the process, leading to inconsistent drug effectiveness.

Gene activation · Dossier · The Nexus