clinical trials
Coverage of clinical trials in the Nexus archive.
- Is China’s biotech boom at risk? Fear of policy backlash after death in gene-editing trial
A six-year-old girl died after receiving an experimental gene-editing therapy, prompting calls for improved trial safeguards. The biotechnology industry fears Chinese policymakers may reduce regulatory flexibility, which has been critical to China's competitive edge in frontier treatments.
- Prediction market wagering on drug approvals draws fire from researchers
Betting platforms Kalshi and Polymarket are allowing users to wager on FDA drug approvals and clinical trial outcomes, sparking criticism from researchers, doctors, and patients over risks to scientific integrity and public trust. Critics argue prediction markets could influence trial behavior and enable insider trading, while Kalshi claims they offer valuable insights and have safeguards against insider participation.
- Clinical Failure Rates over the Decades: Yikes
The article discusses clinical trial failure rates over decades, highlighting concerns about their increasing trends. It references data from a Science.org blog post and includes Hacker News comments with 15 points and 9 discussions.
- STAT+: Kalshi comes for biopharma, with prediction markets for clinical trials and FDA approvals
Kalshi, a major prediction market exchange, will launch markets for betting on clinical trials and FDA approvals in collaboration with tech partner AppliedXL. The initiative expands prediction markets into the biopharma industry, focusing on clinical trial outcomes and regulatory decisions.
- Blood test may detect Alzheimer’s risk in healthy people, study finds
A blood test may detect Alzheimer’s risk in healthy individuals, according to a study. Large clinical trials are currently testing whether drugs can prevent or delay the disease, with a need for an easy method to identify suitable candidates.
- UK launches national dementia registry to speed up search for treatments
The UK has launched a national dementia registry aimed at accelerating the search for treatments. The initiative seeks to improve access to clinical trials and attract more life sciences investment to the country.
- Congress is investigating Merck and AbbVie over drug trials in China tied to its military
Congress is investigating Merck and AbbVie over clinical trials conducted in China, specifically at military facilities and in Xinjiang. A bipartisan House committee has requested details on hundreds of these studies.
- STAT+: FDA to launch pilot program to speed up early-stage clinical trials
Federal health officials announced a pilot program to accelerate early-stage clinical trials by six to 12 months, aiming to boost U.S.-based research and counter Chinese dominance. The initiative, part of a 2027 fiscal budget proposal, was supported by former FDA Commissioner Marty Makary and endorsed by Health Secretary Robert F. Kennedy Jr. in a Fox News op-ed.
- FIRST AID: Parliament puts wastewater rules on hold
Parliament has delayed wastewater rules. The article also covers topics related to tobacco, clinical trials, and nutri score.
- Proposed White House regulations could kill 5,000 clinical trials, analysis finds
Proposed White House regulations could eliminate 5,000 clinical trials by granting political appointees final authority over research grants.
- NJ Alzheimer's Town Hall: Why Clinical Trials May Hold the Key to a Cure
The article discusses an Alzheimer's town hall in Tenafly, New Jersey, highlighting the potential role of clinical trials in finding a cure. Reporter Nina Pineda provided details on the event.
- FIRST AID: Biotech negotiators push faster trials
Biotech negotiators are advocating for accelerated clinical trials. The article also mentions an AI tobacco campaign and references SPC.
- Pharma giant Novo Nordisk discloses breach of clinical trials data
Danish pharmaceutical giant Novo Nordisk disclosed a data breach affecting patient information from some clinical trials. The breach impacts data related to clinical trials conducted by the company.
- Watch live: Reimagining Clinical Trials – Expanding Access by Meeting Patients Where They Are
Clinical trials are underutilized in healthcare, limiting patient access and slowing enrollment. They are often seen as a last resort rather than a viable care option. Expanding access to clinical trials can improve patient care and innovative therapies.
- Fecal transplants for autism deliver success in clinical trials
Fecal transplants have shown success in clinical trials for treating autism, with positive results reported. The treatment involves transplanting fecal matter from a donor into a patient. Clinical trials have demonstrated promising outcomes.
- Why Has There Been So Little Progress on Alzheimer's Disease?
The article examines the lack of significant progress in Alzheimer's disease research, highlighting challenges such as funding gaps, complex pathology, and failed drug trials. It questions why breakthroughs remain elusive despite increased attention and resources.