Dossier
DNA repair
Coverage of DNA repair in the Nexus archive.
- Repairing DNA damage: Scientists discover a surprising new benefit of melatonin
A new study suggests melatonin supplements may enhance DNA repair processes in night shift workers, potentially reducing health risks linked to overnight work. The findings indicate a possible simple strategy to mitigate long-term damage from night shifts.
- αKG-mediated carnitine synthesis drives DNA repair via histone acetylation
The metabolite αKG promotes carnitine synthesis and site-specific histone acetylation, enhancing homologous recombination-mediated DNA repair. This mechanism may offer therapeutic potential for chemoresistant cancers.