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histone acetylation

Coverage of histone acetylation in the Nexus archive.

Earliest in view: May 27 · 00:00 UTCMost recent: May 27 · 00:00 UTC

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HEALTHMay 27 · 00:00 UTCNATURE NEWS
αKG-mediated carnitine synthesis drives DNA repair via histone acetylation
The metabolite αKG promotes carnitine synthesis and site-specific histone acetylation, enhancing homologous recombination-mediated DNA repair. This mechanism may offer therapeutic potential for chemoresistant cancers.